Wallenberg Clinical Scholars 2016

The Knut and Alice Wallenberg Foundation is investing almost SEK 600 million over a ten-year period in the research programme Wallenberg Clinical Scholars. The programme provides funding for 25 of the country’s foremost clinical researchers.

The aim of the programme is to strengthen Swedish clinical research by means of identifying the best clinical researchers, providing them with good conditions to undertake their work, and facilitate the impact of research results in the scientific and healthcare communities.

Wallenberg Clinical Scholars is part of a ten-year initiative amounting to a total of SEK 1.7 billion, undertaken by the Knut and Alice Wallenberg Foundation to strengthen medical research and the life sciences.

Wallenberg Clinical Scholars 2016:

Olle Melander, Senior Physician and Professor at the Department of Clinical Sciences, Lund University, has found several biomarkers in the body that better predict whether someone will develop cardiovascular disease. As a Wallenberg Clinical Scholar, he will investigate whether these markers could be directly involved in the development of the disease by studying whether people with genetically raised levels more frequently suffer from cardiovascular problems.
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Claes Ohlsson, Senior Physician and Professor at the Institute of Medicine, University of Gothenburg, has used large-scale methodology for genetic analysis to identify genetic changes that increase the risk of osteoporosis. In these genetic clues, he has succeeded in identifying proteins in the body that directly increase the risk of bone fractures. As a Wallenberg Clinical Scholar, Claes Ohlsson will study these proteins in detail. How do they protect against bone fractures? Is it possible to develop a pharmaceutical that boosts their positive effects?
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Diana Karpman, Senior Physician and Professor at the Department of Clinical Sciences, Lund University, is studying the molecular mechanisms that cause kidney failure. As a Wallenberg Clinical Scholar, she will investigate whether vesicles can carry inflammatory substances to the kidneys. She will try to find substances that can stop various harmful vesicles from forming and which may inhibit the dangerous immune reaction in the kidneys. Treatments that save the kidneys can extend the life of patients by many years. 
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Per Svenningsson, Deputy Chief Physician in Neurology and Professor at the Department of Clinical Neuroscience, Karolinska Institutet, studies the proteins that are central in the development of Parkinson’s disease. As a Wallenberg Clinical Scholar, he will also investigate pharmaceuticals that can potentially protect the brain cells from damage. There are currently medicines that can lessen the symptoms of the disease, but none that can stop its destructive progression.
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Miia Kivipelto, Professor at the Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, has shown that it is possible to prevent memory problems through a number of measures, including dietary changes, physical training, cognitive training and the normalization of blood pressure and blood lipids. As a Wallenberg Clinical Scholar she will, among other things, develop a platform for high-quality clinical studies of dementia. Her work also includes developing models for assessing a person’s risk of dementia, investigating which mechanisms drive the disease and how these can be counteracted through a range of measures. 
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